Towards Understanding the Clinical Signi�icance of QT Peak Prolongation- A Novel Marker of Myocardial Ischemia Independently Demonstrated in Two Prospective Studies

Preventing cardiac deaths remains one of the greatest challenges in medicine in the 21st Century. There is evidence to suggest QT peak prolongation identi�ies patients who are at risk of death or non-fatal myocardial infarction (MI) [1]. The next step to reduce the risk of these patients would be to �ind out whether there are potentially treatable conditions associated with QT peak prolongation. A potential mechanism by which QT peak prolongation might predict death or non-fatal MI might be that QT peak prolongation is associated with myocardial ischaemia. In this paper, we will test the hypothesis that QT peak prolongation is associated with myocardial ischaemia.